x_TransfusionMedicineMadeEasy4StudentsBiomedicalITO12.pdf

osaro erhabor

Teddy charles adias

Transfusion Medicine

Made easy for sTudenTs

of allied Medical

sciences and Medicine

Transfusion Medicine

Made easy for sTudenTs

of allied Medical

sciences and Medicine

Authored by osaro erhabor and

Teddy charles adias

Transfusion Medicine Made Easy for Students of Allied Medical Sciences and Medicine

Authored by: Dr Osaro Erhabor (Ph.D, CSci, FIBMS) and Dr Teddy Charles Adias (Ph.D, FIBMS)

Published by InTech

Janeza Trdine 9, 51000 Rijeka, Croatia

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Notice

Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the

editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The

publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials,

instructions, methods or ideas contained in the book.

Publishing Process Manager Silvia Vlase

Typesetting InTech DTP Team

Cover Design InTech Design Team

First Published May, 2012

Printed in Croatia

A free online edition of this book is available at www.intechopen.com

Additional hard copies can be obtained from orders@intechopen.com

Transfusion Medicine Made Easy for Students of Allied Medical Sciences and Medicine

Authored by: Dr Osaro Erhabor (Ph.D, CSci, FIBMS) and Dr Teddy Charles Adias (Ph.D, FIBMS)

p. cm.

ISBN 978-953-51-0523-7

Contents

Acknowledgements 1

1. History of Blood Transfusion 2

2. Antigen and Antibody 4

3. Blood Group Systems and ABO groups 20

4. Anticoagulation and Preservation in Transfusion 49

5. Blood Donation Testing 54

6. Apheresis Principle and Practice 59

7. Blood Component Preparation 60

8. Challenges of Blood Transfusion in Africa 66

9. Blood Donation and Donor Types 68

10. Advantages of Autologous Blood over Allogeneic Blood 72

11. Transfusion Transmissible Infectious Diseases 79

12. Complications of Blood Transfusion 83

13. Investigation of Blood Transfusion Reactions 90

14. Compatibility Testing 92

15. Red Blood Cells Alloimmunisation 100

16. HDFN and Management of Rh Negative Pregnancies 115

17. Transfusion Alternatives and Exemplary Stewardship in the Management

of Blood and Blood Product 128

18. Blood Components Therapy 133

19. Management of Major Haemorrhage 143

20. Storage Conditions, Shelf Life Indication and Mode of Transfusion 147

22. Fractionated Plasma Products 158

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